Pleural effusion due to left-heart failure is an exception to this rule, in which the fluid comes from the visceral pleura. The parietal side of the pleura accounts for most of the production of pleural fluid, and for most of its resorption as well. The mean rate of both the production and the absorption of pleural fluid is normally 0.2 mL/kg/hr, which implies that the entire volume of the pleural fluid normally turns over within one hour ( 2). The causes of pleural effusion vary widely, ranging from fairly harmless effusions accompanying viral pleuritis to prognostically highly relevant ones due to congestive heart failure or cancer.īoth the visceral and the parietal pleura play an important role in fluid homeostasis in the pleural space.
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